Thiourea → HCID 54190067, compound

HRID 974307Notes

Reaction equation

HRID 974307 reaction equation
Br.Br[CH:3]1[CH2:9][CH2:8][N:7]([CH2:10][C:11]#[C:12][C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[CH2:6][CH2:5][C:4]1=O.[NH2:20][C:21]([NH2:23])=[S:22]>C(O)C>[NH2:23][C:21]1[S:22][C:4]2[CH2:5][CH2:6][N:7]([CH2:10][CH:11]=[CH:12][C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)[CH2:8][CH2:9][C:3]=2[N:20]=1

Participants

4

Reactant 2

HCID 2723790ThioureaHCID 19985742HCID 19985742, compound

Product 1

HCID 54190067HCID 54190067, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Prepared from 5-bromo-1-(3-phenyl-2-propyn-1-yl)-hexahydro-4H-azepin-4-one hydrobromide by reacting with thiourea in ethanol. Yield: 4% of theory, Melting point: 145°-148° C.

Sources & evidence

ORD record
ord-466458c1c2204cd88cb31c693ab04a75
Source dataset
uspto-grants-1991_11
Patent number
US05068325

Reaction notes

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