2-Amino-4,5,6,7,8-pentahydrothiazolo[5,4-d]azepine → HCID 53978307, compound

HRID 974312Notes

Reaction equation

HRID 974312 reaction equation
[CH3:1][O:2][C:3]1[CH:12]=[CH:11][CH:10]=[CH:9][C:4]=1[CH:5]=[CH:6][CH2:7]Cl.[NH2:13][C:14]1[S:15][C:16]2[CH2:17][CH2:18][NH:19][CH2:20][CH2:21][C:22]=2[N:23]=1>C(Cl)(Cl)Cl>[NH2:13][C:14]1[S:15][C:16]2[CH2:17][CH2:18][N:19]([CH2:7][CH:6]=[CH:5][C:4]3[CH:9]=[CH:10][CH:11]=[CH:12][C:3]=3[O:2][CH3:1])[CH2:20][CH2:21][C:22]=2[N:23]=1

Participants

4

Reactant 2

HCID 199857852-Amino-4,5,6,7,8-pentahydrothiazolo[5,4-d]azepineHCID 54291384HCID 54291384, compound

Product 1

HCID 53978307HCID 53978307, compoundYield 13%

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

Prepared from 2-methoxy-cinnamyl chloride and 2 equivalents of 2-amino-4,5,7,8-tetrahydro-6H-thiazolo[5,4-d]azepine in chloroform. Yield: 13% of theory, Melting point: 80°-84° C.

Sources & evidence

ORD record
ord-86300bd7508040e69ca3d692d088435d
Source dataset
uspto-grants-1991_11
Patent number
US05068325

Reaction notes

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