2-Amino-4,5,6,7,8-pentahydrothiazolo[5,4-d]azepine → HCID 54332195, compound

HRID 974313Notes

Reaction equation

HRID 974313 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:10]=[CH:11][CH:12]=1)[CH:6]=[CH:7][CH2:8]Cl.[NH2:13][C:14]1[S:15][C:16]2[CH2:17][CH2:18][NH:19][CH2:20][CH2:21][C:22]=2[N:23]=1>C(Cl)(Cl)Cl>[NH2:13][C:14]1[S:15][C:16]2[CH2:17][CH2:18][N:19]([CH2:8][CH:7]=[CH:6][C:5]3[CH:10]=[CH:11][CH:12]=[C:3]([O:2][CH3:1])[CH:4]=3)[CH2:20][CH2:21][C:22]=2[N:23]=1

Participants

4

Reactant 2

HCID 199857852-Amino-4,5,6,7,8-pentahydrothiazolo[5,4-d]azepineHCID 54182336HCID 54182336, compound

Product 1

HCID 54332195HCID 54332195, compoundYield 21%

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

Prepared from 3-methoxy-cinnamyl chloride and 2 equivalents of 2-amino-4,5,7,8-tetrahydro-6H-thiazolo[5,4-d]azepine in chloroform. -Yield: 21% of theory, Melting point: 120°-124° C.

Sources & evidence

ORD record
ord-8ebd457335524cababc0db8bd883a8c6
Source dataset
uspto-grants-1991_11
Patent number
US05068325

Reaction notes

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