Diethyl Ether → HCID 86745240, compound

HRID 974314Notes

Reaction equation

HRID 974314 reaction equation
[CH3:1][S:2]([C:4]1[CH:13]=[CH:12][C:7]([CH:8]=[CH:9][CH2:10]Cl)=[CH:6][CH:5]=1)=[O:3].[NH2:14][C:15]1[S:16][C:17]2[CH2:18][CH2:19][NH:20][CH2:21][CH2:22][C:23]=2[N:24]=1.CCOCC>C(Cl)(Cl)Cl>[OH2:3].[NH2:14][C:15]1[S:16][C:17]2[CH2:18][CH2:19][N:20]([CH2:10][CH:9]=[CH:8][C:7]3[CH:12]=[CH:13][C:4]([S:2]([CH3:1])=[O:3])=[CH:5][CH:6]=3)[CH2:21][CH2:22][C:23]=2[N:24]=1

Participants

5

Reactant 3

HCID 3283Diethyl EtherHCID 199857852-Amino-4,5,6,7,8-pentahydrothiazolo[5,4-d]azepineHCID 53637586HCID 53637586, compound

Product 1

HCID 86745240HCID 86745240, compoundYield 48%

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

Prepared from 4-methylsulphinyl-cinnamyl chloride and 2 equivalents of 2-amino-4,5,7,8-tetrahydro-6H-thiazolo[5,4-d]azepine in chloroform. Yield: 48% of theory, Melting point: 171°-176° C. (ether).

Sources & evidence

ORD record
ord-fae41ac2faf24ce0b252861f5bb6ff0d
Source dataset
uspto-grants-1991_11
Patent number
US05068325

Reaction notes

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