2-Amino-4,5,6,7,8-pentahydrothiazolo[5,4-d]azepine → HCID 86745241, compound

HRID 974317Notes

Reaction equation

HRID 974317 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:10]=[C:11]([O:15][CH3:16])[C:12]=1[O:13][CH3:14])[CH:6]=[CH:7][CH2:8]Cl.[NH2:17][C:18]1[S:19][C:20]2[CH2:21][CH2:22][NH:23][CH2:24][CH2:25][C:26]=2[N:27]=1>C(Cl)(Cl)Cl>[OH2:2].[NH2:17][C:18]1[S:19][C:20]2[CH2:21][CH2:22][N:23]([CH2:8][CH:7]=[CH:6][C:5]3[CH:4]=[C:3]([O:2][CH3:1])[C:12]([O:13][CH3:14])=[C:11]([O:15][CH3:16])[CH:10]=3)[CH2:24][CH2:25][C:26]=2[N:27]=1

Participants

4

Reactant 2

HCID 199857852-Amino-4,5,6,7,8-pentahydrothiazolo[5,4-d]azepineHCID 54557719HCID 54557719, compound

Product 1

HCID 86745241HCID 86745241, compoundYield 17%

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

Prepared from 3,4,5-trimethoxy-cinnamyl chloride and 2 equivalents of 2-amino-4,5,7,8-tetrahydro-6H-thiazolo[5,4-d]azepine in chloroform. Yield: 17% of theory, Melting point: 70°-73° C. (decomp.)

Sources & evidence

ORD record
ord-3f58e118b65e4269a8f28805ab78256b
Source dataset
uspto-grants-1991_11
Patent number
US05068325

Reaction notes

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