Diethyl Ether → HCID 54555387, compound

HRID 974320Notes

Reaction equation

HRID 974320 reaction equation
Cl.[CH3:2][C:3]1[C:4]([CH:9]=[CH:10][CH2:11]Cl)=[N:5][CH:6]=[CH:7][CH:8]=1.[NH2:13][C:14]1[S:15][C:16]2[CH2:17][CH2:18][NH:19][CH2:20][CH2:21][C:22]=2[N:23]=1.CCOCC>C(Cl)(Cl)Cl>[NH2:13][C:14]1[S:15][C:16]2[CH2:17][CH2:18][N:19]([CH2:11][CH:10]=[CH:9][C:4]3[C:3]([CH3:2])=[CH:8][CH:7]=[CH:6][N:5]=3)[CH2:20][CH2:21][C:22]=2[N:23]=1

Participants

5

Reactant 3

HCID 3283Diethyl EtherHCID 199857852-Amino-4,5,6,7,8-pentahydrothiazolo[5,4-d]azepineHCID 70045288HCID 70045288, compound

Product 1

HCID 54555387HCID 54555387, compoundYield 45%

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

Prepared from 3-(3-methyl-2-pyridyl)allyl chloride hydrochloride and 3 equivalents of 2-amino-4,5,7,8-tetrahydro-6H-thiazolo[5,4-d]azepine in chloroform. Yield: 45% of theory, Melting point: 188°-190° C. (ether).

Sources & evidence

ORD record
ord-5effa93a356d4fcf88c95f5047298816
Source dataset
uspto-grants-1991_11
Patent number
US05068325

Reaction notes

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