Diethyl Ether → HCID 54180039, compound

HRID 974322Notes

Reaction equation

HRID 974322 reaction equation
Cl.[CH3:2][C:3]1[N:8]=[CH:7][C:6]([CH:9]=[CH:10][CH2:11]Cl)=[CH:5][CH:4]=1.[NH2:13][C:14]1[S:15][C:16]2[CH2:17][CH2:18][NH:19][CH2:20][CH2:21][C:22]=2[N:23]=1.CCOCC>C(Cl)(Cl)Cl>[NH2:13][C:14]1[S:15][C:16]2[CH2:17][CH2:18][N:19]([CH2:11][CH:10]=[CH:9][C:6]3[CH:7]=[N:8][C:3]([CH3:2])=[CH:4][CH:5]=3)[CH2:20][CH2:21][C:22]=2[N:23]=1

Participants

5

Reactant 3

HCID 3283Diethyl EtherHCID 199857852-Amino-4,5,6,7,8-pentahydrothiazolo[5,4-d]azepineHCID 70047528HCID 70047528, compound

Product 1

HCID 54180039HCID 54180039, compoundYield 30%

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

Prepared from 3-(6-methyl-3-pyridyl)allyl chloride hydrochloride and 3 equivalents of 2-amino-4,5,7,8-tetrahydro-6H-thiazolo[5,4-d]azepine in chloroform. Yield: 30% of theory, Melting point: 180°-184° C. (ether).

Sources & evidence

ORD record
ord-b9df78e1524743d19f4286ea57676335
Source dataset
uspto-grants-1991_11
Patent number
US05068325

Reaction notes

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