反应详情

温度

130 °C

2-Hexadecylsuccinic anhydride (10.5 g, 31.3 mmol), 3-(3,5-di-t-butyl-4-hydroxyphenyl)propanoic acid hydrazide (9.2 g, 31.3 mmol) and 10 ml of toluene were combined and refluxed for one hour under a nitrogen atmosphere with the azeotropic removal of water. Solvent was then removed under vacuum as the mixture was warmed to about 130° C. After 20 minutes, the reaction mixture was cooled and the vacuum was removed. The resulting viscous yellow mass was further chilled in an acetone/dry ice bath causing the mass to harden for facile removal from the reaction vessel. About 19 g of a viscous yellow gum was obtained that solidified to a translucent white solid upon standing for several days at room temperature.

1. customSolvent was then removed under vacuum as the mixture
2. temperaturethe reaction mixture was cooled
3. customthe vacuum was removed
4. temperatureThe resulting viscous yellow mass was further chilled in an acetone/dry ice bath
5. customto harden for facile removal from the reaction vessel