HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzaldehyde → N-Benzylidene-2,4-difluorobenzylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzaldehyde | HCID 240 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | 2,4-Difluorobenzylamine | HCID 2733244 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | N-Benzylidene-2,4-difluorobenzylamine | HCID 19986446 | — |
Reaction Steps
50.2 g (0.35 mol) of 2,4-difluorobenzylamine and 37.1 g (0.35 mol) of benzaldehyde are dissolved in 140 ml of toluene and heated to reflux. The water produced is separated off using a water separator. The reaction is complete (GC check) after two hours. The solution is evaporated on a vacuum rotary evaporator. 78.9 g (97% of theory) of a slightly yellow liquid are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05068371 |
| Source dataset | uspto-grants-1991_11 |
| ORD ID | ord-6267607942ce40488e1d03f6daa5f76d |
| Source note | uspto-grants-1991_11 |