Trimethyl phosphite → HCID 14423944, compound

Participants

Reaction Steps

A slurry of 3,3-bis-(4-fluorophenyl)-1-bromo-2-(1-methyl-1H-tetrazol-5-yl)-2-propene (1.17 g, 3.0 mmol) and trimethyl phosphite (0.41 g, 3.3 mmol) was heated at 100° C. for 5 minutes. After cooling to ambient temperature, excess trimethylphosphite was removed in vacuo to give a light yellow solid. This solid was recrystallized from ethyl-acetate/hexane mixture to give the title compound as a pure white solid; m.p.=140°-141° C.

Provenance & Evidence