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HRID974533

反应详情

EQUATION

反应方程式

HRID 974533 的结构方程式

REACTANTS

反应物

2
结构：O
HCID962

Water

H2O

结构：CC(C)CC(N(C)C)C1(c2ccc(Cl)cc2)CCC1.Cl
HCID64764

Sibutramine hydrochloride

C17H27Cl2N

PRODUCTS

生成物

1
结构：CC(C)CC(N(C)C)C1(c2ccc(Cl)cc2)CCC1.Cl.O
HCID64765

1-[1-(4-Chlorophenyl)cyclobutyl]-N,N,3-trimethylbutan-1-amine--hydrogen chloride--water (1/1/1)

C17H29Cl2NO

PROCEDURE

实验过程

A sample (48.2 g) of N,N-dimethyl-1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutylamine hydrochloride was suspended and stirred with water (145 ml) for 24 hours at 25° C. The solid was collected by filtration and dried by suction at ambient temperature to give N,N-dimethyl-1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutylamine hydrochloride monohydrate (m.p. 191°-195.5° C.).

WORKUP

后处理

  1. filtrationThe solid was collected by filtration
  2. customdried by suction at ambient temperature