1-Methylimidazole → HCID 178442848, compound

HRID 974679Notes

Reaction equation

[P:1]([O-:39])([O:35][CH2:36][CH2:37]Br)([O:3][CH2:4][CH:5]([O:29][C:30]1[CH:34]=[CH:33][O:32][N:31]=1)[CH2:6][O:7][C:8]1[CH:12]=[C:11]([CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28])[O:10][N:9]=1)=[O:2].[CH3:40][N:41]1[CH:45]=[CH:44][N:43]=[CH:42]1>>[P:1]([O-:39])([O:35][CH2:36][CH2:37][N+:43]1[CH:44]=[CH:45][N:41]([CH3:40])[CH:42]=1)([O:3][CH2:4][CH:5]([O:29][C:30]1[CH:34]=[CH:33][O:32][N:31]=1)[CH2:6][O:7][C:8]1[CH:12]=[C:11]([CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28])[O:10][N:9]=1)=[O:2]

Participants

Reactant 2

HCID 13901-Methylimidazole

HCID 19986072HCID 19986072, compound

Product 1

HCID 178442848HCID 178442848, compound

Procedure

21(b) Following the procedure described in Example 17, 0.730 g of (2RS)-3-(5-hexadecyl-3-isoxazolyloxy)-2-(3-isoxazolyloxy)propyl 2-bromoethyl phosphate [prepared as described in step (a) above] was reacted with 0.91 ml of N-methylimidazole, to give 0.477 g of the title compound as a pale-yellow resinous material.

Sources & evidence

ORD record: ord-c287f03164814d8d9ddd96cae9239955
Source dataset: uspto-grants-1991_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05068340

Reaction notes

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