Benzyl Alcohol → HCID 19969644, compound

Participants

Reaction Steps

The acid of step (a) (25 g), triethylamine (11.2 ml) and diphenylphosphoryl azide were dissolved in dry toluene (400 ml) and heated at reflux for 3 hours. Benzyl alcohol (30.4 ml) was added dropwise and the resulting mixture was refluxed overnight. Concentration of the reaction mixture afforded a dark oil which was purified by chromatography on silica gel and elution with ethyl acetate/hexanes [1:9-1:1]to give the subtitle compound (25 g).

Provenance & Evidence