HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Benzyl-octahydropyrrolo[3,4-b][1,4]oxazine → Octahydropyrrolo[3,4-b][1,4]oxazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Benzyl-octahydropyrrolo[3,4-b][1,4]oxazine | HCID 15069980 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Octahydropyrrolo[3,4-b][1,4]oxazine | HCID 15069981 | — |
Reaction Steps
7.2 g (33 mmol) of 8-benzyl-2-oxa-5,8-diazabicyclo-[4.3.0]nonane are hydrogenated in 400 ml of methanol with 2.5 g of palladium-on-active charcoal (10% of Pd) under 50 bar at 100° C. The catalyst is filtered off with suction, the filtrate is concentrated and the residue is distilled.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05607942 |
| Source dataset | uspto-grants-1997_03 |
| ORD ID | ord-406c9d82f6e647afb643d65bc0b2c189 |
| Source note | uspto-grants-1997_03 |