HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tetrahydro-6-(phenylmethyl)-1H-pyrrolo(3,4-b)pyridine-5,7(2H,6H)-dione → 6-Benzyloctahydro-1H-pyrrolo[3,4-b]pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tetrahydro-6-(phenylmethyl)-1H-pyrrolo(3,4-b)pyridine-5,7(2H,6H)-dione | HCID 9899604 | — |
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 6-Benzyloctahydro-1H-pyrrolo[3,4-b]pyridine | HCID 11356376 | — |
Reaction Steps
44 g (about 0.18 mol ) of crude or pure 6-benzyl-5,7-dioxo-octahydropyrrolo[3,4-b]pyridine are reduced with 15.2 g (0.40 mol ) of lithium aluminum hydride in 390 ml of absolute tetrahydrofuran in the course of 10 hours in accordance ,with the working instructions of Example Ic. 24.4 g of a colorless oil having a boiling point of 93°-95° C./0.06 mbar are obtained on distillation.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05607942 |
| Source dataset | uspto-grants-1997_03 |
| ORD ID | ord-e1a125ff3382415c9802b8ff8a4bb1b3 |
| Source note | uspto-grants-1997_03 |