HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 178471933, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | 2,4-Difluoroaniline | HCID 9709 | — |
| Reactant | Ethyl 3-ethoxy-2-(2,3,4,5,6-pentafluorobenzoyl)-acrylate | HCID 53952225 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178471933 | HCID 178471933 | 94.5% |
Reaction Steps
44.3 g of 2,4-difluoroaniline are added dropwise to a solution of 115 g of ethyl 3-ethoxy-2-(2,3,4,5,6-pentafluorobenzoyl)-acrylate in 380 ml of ethanol, while cooling with ice and stirring. The mixture is stirred at room temperature for 1 hour, 380 ml of water are added, while cooling with ice, and the precipitate is filtered off with suction, washed with ethanol/H2O (1:1) and dried. 135.4 g of the title compound of melting point 97°-99° C. are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05607942 |
| Source dataset | uspto-grants-1997_03 |
| ORD ID | ord-f0c24fb66ed2421cbfdf6bac5f4078cd |
| Source note | uspto-grants-1997_03 |