HCID 19970179, compound → HCID 19970188, compound

HRID 974968Notes

Reaction equation

HRID 974968 reaction equation
[Br-:1].[Cl:2][C:3]1[CH:32]=[CH:31][C:6]([CH2:7][CH2:8][N+:9]2[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=2[CH2:15][C:16]([C:29]#[N:30])([C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)[C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[CH:5][CH:4]=1.[H][H]>CO.[Pt]=O>[BrH:1].[Cl:2][C:3]1[CH:4]=[CH:5][C:6]([CH2:7][CH2:8][N:9]2[CH2:14][CH2:13][CH2:12][CH2:11][CH:10]2[CH2:15][C:16]([C:29]#[N:30])([C:23]2[CH:24]=[CH:25][CH:26]=[CH:27][CH:28]=2)[C:17]2[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=2)=[CH:31][CH:32]=1

Participants

5

Reactant 2

HCID 19970179HCID 19970179, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 19970188HCID 19970188, compoundYield 100%

Reagents, catalysts & solvents 2

HCID 82844Platinum oxide (PtO)CatalystHCID 887MethanolSolvent

Procedure

A solution of 1-(4-chlorophenethyl)-2-(2-cyano-2,2-diphenylethyl)pyridinium bromide (252 mg, 0.50 mmol) (see Preparation 4) in methanol (3 ml) was stirred at room temperature under one atmosphere of hydrogen in the presence of platinum oxide (20 mg) for 3 hours, filtered and evaporated to give the title compound (255 mg, 100%) as a colourless foam.

Workup

  1. filtrationfiltered
  2. customevaporated

Sources & evidence

ORD record
ord-b17cc7f24cba44099b2c2e6e5d911f8a
Source dataset
uspto-grants-1997_03
Patent number
US05607950

Reaction notes

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