4-Methylthiazole → 1-(2-Furyl)-1-(4-methyl-5-thiazolyl)ethanol

HRID 975059Notes

Reaction equation

[CH3:1][C:2]1[N:3]=[CH:4][S:5][CH:6]=1.[C:7]([C:10]1[O:11][CH:12]=[CH:13][CH:14]=1)(=[O:9])[CH3:8]>>[O:11]1[CH:12]=[CH:13][CH:14]=[C:10]1[C:7]([C:6]1[S:5][CH:4]=[N:3][C:2]=1[CH3:1])([OH:9])[CH3:8]

Participants

Reactant 2

HCID 127484-Methylthiazole

HCID 145052-Acetylfuran

Product 1

HCID 189363561-(2-Furyl)-1-(4-methyl-5-thiazolyl)ethanol

Procedure

Starting with 4-methylthiazole and 2-acetylfuran and following the general method of Example 15 the title compound was prepared. M.p. 127°-128° C.

Sources & evidence

ORD record: ord-863e9ec5a6dc47bf885ca6eb2ce39e44
Source dataset: uspto-grants-1997_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05607956

Reaction notes

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