4-Methylthiazole → 2-(4-Methyl-2-thiazolyl)-2-(2-thienyl)tetrahydrofuran

HRID 975070Notes

Reaction equation

[CH3:1][C:2]1[N:3]=[CH:4][S:5][CH:6]=1.Cl[CH2:8][CH2:9][CH2:10][C:11]([C:13]1[S:14][CH:15]=[CH:16][CH:17]=1)=[O:12]>>[CH3:1][C:2]1[N:3]=[C:4]([C:11]2([C:13]3[S:14][CH:15]=[CH:16][CH:17]=3)[CH2:10][CH2:9][CH2:8][O:12]2)[S:5][CH:6]=1

Participants

Reactant 2

HCID 127484-Methylthiazole

HCID 1235114-Chloro-1-(2-thienyl)butan-1-one

Product 1

HCID 189363032-(4-Methyl-2-thiazolyl)-2-(2-thienyl)tetrahydrofuran

Procedure

The title compound was prepared from 4-methylthiazole and 4-chloro-1-(2-thienyl)-1-butanone, using the general method of Example 36.

Sources & evidence

ORD record: ord-ea2ec9364a654048a494515ad649425b
Source dataset: uspto-grants-1997_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05607956

Reaction notes

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