2,6-Difluorobenzamide → HCID 13749711, compound

HRID 975134Notes

Reaction equation

HRID 975134 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([N:10]=[C:11]=[O:12])[CH:5]=[C:6]([Cl:9])[C:7]=1[Cl:8].[F:13][C:14]1[CH:22]=[CH:21][CH:20]=[C:19]([F:23])[C:15]=1[C:16]([NH2:18])=[O:17]>C1(C)C=CC=CC=1>[Cl:1][C:2]1[CH:3]=[C:4]([NH:10][C:11]([NH:18][C:16](=[O:17])[C:15]2[C:14]([F:13])=[CH:22][CH:21]=[CH:20][C:19]=2[F:23])=[O:12])[CH:5]=[C:6]([Cl:9])[C:7]=1[Cl:8]

Participants

4

Reactant 2

HCID 874392,6-DifluorobenzamideHCID 145450443,4,5-Trichlorophenylisocyanate

Product 1

HCID 13749711HCID 13749711, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

A solution of 3,4,5-trichloro-phenyl isocyanate (22.3 g), 2,6-difluoro-benzamide (15.7 g) in toluene (200 ml) was heated for eight hours at 90°-95° C. The title compound slowly crystallized out of the initially clear solution and was isolated by suction filtration after cooling of the reaction mixture.

Workup

  1. customThe title compound slowly crystallized out of the initially clear solution
  2. customwas isolated by suction filtration
  3. temperatureafter cooling of the reaction mixture

Sources & evidence

ORD record
ord-6ad7e54b6e934a29b0caa341a919ba7b
Source dataset
uspto-grants-1997_03
Patent number
US05607977

Reaction notes

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