HCID 53703279, compound → HCID 22870336, compound

HRID 975137Notes

Reaction equation

HRID 975137 reaction equation
[OH:1][CH2:2][CH2:3][CH:4]=[CH:5][C:6]1[CH:7]=[C:8]2[C:12](=[CH:13][CH:14]=1)[NH:11][CH:10]=[C:9]2[CH2:15][C@H:16]1[CH2:20][CH2:19][CH2:18][N:17]1[CH3:21]>[Pd].C(Cl)Cl>[OH:1][CH2:2][CH2:3][CH2:4][CH2:5][C:6]1[CH:7]=[C:8]2[C:12](=[CH:13][CH:14]=1)[NH:11][CH:10]=[C:9]2[CH2:15][C@H:16]1[CH2:20][CH2:19][CH2:18][N:17]1[CH3:21]

Participants

4

Reactant 1

HCID 53703279HCID 53703279, compound

Product 1

HCID 22870336HCID 22870336, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 6344DichloromethaneSolvent

Procedure

Obtained from the title compound of Example 17 by a procedure similar to that described in Example 2, but using 10% palladium on charcoal as catalyst, as a foam. Rf 0.14 (SS 7). Found: C,71.04; H,8.27; N,8.61. C18H26N2O; 0.33 CH2Cl2 requires C,70.47; H,8.59; N,8.97%.

Sources & evidence

ORD record
ord-d06e2dabeee34156953bc649733a45e5
Source dataset
uspto-grants-1997_03
Patent number
US05607960

Reaction notes

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