HCID 53677731, compound → HCID 22870283, compound

HRID 975149Notes

Reaction equation

HRID 975149 reaction equation
[CH3:1][N:2]1[CH2:6][CH2:5][CH2:4][C@@H:3]1[CH2:7][C:8]1[C:16]2[C:11](=[CH:12][CH:13]=[C:14]([CH:17]=[CH:18][C:19](=[O:22])[CH2:20][CH3:21])[CH:15]=2)[NH:10][CH:9]=1>[Pd].O>[CH3:1][N:2]1[CH2:6][CH2:5][CH2:4][C@@H:3]1[CH2:7][C:8]1[C:16]2[C:11](=[CH:12][CH:13]=[C:14]([CH2:17][CH2:18][C:19](=[O:22])[CH2:20][CH3:21])[CH:15]=2)[NH:10][CH:9]=1

Participants

4

Reactant 1

HCID 53677731HCID 53677731, compound

Product 1

HCID 22870283HCID 22870283, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 962WaterSolvent

Procedure

Obtained from the title compound of Example 51 by a procedure similar to that described in Example 2, but using 10% palladium on charcoal as catalyst, as a gum. Rf 0.70 (SS 7). [α]D25 +105° (c=0.1, C3OH). Found: C,73.04; H,8.66; N,8.97. C19H26N2O; 0.75 H2O requires C,73.15; H,8.88; N,8.98%.

Sources & evidence

ORD record
ord-b4d629583e804cbb96cef07178a39481
Source dataset
uspto-grants-1997_03
Patent number
US05607960

Reaction notes

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