HCID 54371928, compound → HCID 22870268, compound

HRID 975152Notes

Reaction equation

HRID 975152 reaction equation
[CH3:1][N:2]([CH3:27])[C:3]([CH2:5][CH2:6][N:7]1[CH2:11][CH2:10][CH2:9][C@@H:8]1[CH2:12][C:13]1[C:21]2[C:16](=[CH:17][CH:18]=[C:19]([CH:22]=[CH:23][C:24](=[O:26])[CH3:25])[CH:20]=2)[NH:15][CH:14]=1)=[O:4]>[Pd].CO>[CH3:27][N:2]([CH3:1])[C:3]([CH2:5][CH2:6][N:7]1[CH2:11][CH2:10][CH2:9][C@@H:8]1[CH2:12][C:13]1[C:21]2[C:16](=[CH:17][CH:18]=[C:19]([CH2:22][CH2:23][C:24](=[O:26])[CH3:25])[CH:20]=2)[NH:15][CH:14]=1)=[O:4]

Participants

4

Reactant 1

HCID 54371928HCID 54371928, compound

Product 1

HCID 22870268HCID 22870268, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

Obtained from the title compound of Example 69 by a procedure similar to that described in Example 2, but using 10% palladium on charcoal as catalyst, as a gum. Rf 0.35 (SS 7). [α]D25 +82° (c=0.1, CH3OH). LRMS: m/z 370.6 (M+1)+.

Sources & evidence

ORD record
ord-f2c7013d6ffa43ae99db3719f3e69f70
Source dataset
uspto-grants-1997_03
Patent number
US05607960

Reaction notes

Loading…