HCID 22870268, compound → HCID 22870312, compound

HRID 975153Notes

Reaction equation

HRID 975153 reaction equation
[CH3:1][N:2]([CH3:27])[C:3]([CH2:5][CH2:6][N:7]1[CH2:11][CH2:10][CH2:9][C@@H:8]1[CH2:12][C:13]1[C:21]2[C:16](=[CH:17][CH:18]=[C:19]([CH2:22][CH2:23][C:24](=[O:26])[CH3:25])[CH:20]=2)[NH:15][CH:14]=1)=[O:4]>CO>[OH:26][CH:24]([CH3:25])[CH2:23][CH2:22][C:19]1[CH:20]=[C:21]2[C:16](=[CH:17][CH:18]=1)[NH:15][CH:14]=[C:13]2[CH2:12][C@H:8]1[CH2:9][CH2:10][CH2:11][N:7]1[CH2:6][CH2:5][C:3](=[O:4])[N:2]([CH3:27])[CH3:1]

Participants

3

Reactant 1

HCID 22870268HCID 22870268, compound

Product 1

HCID 22870312HCID 22870312, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Obtained from the title compound of Example 70, by a procedure similar to that described in Example 38, as a foam. Rf 0.28 (SS 7). [α]D25 +51° (c=0.1, CH3OH). Found: C,69.12; H,9.34; N,10.93. C22H33N3O2 ; 0.67 requires C,68.90; H,9.02; N,10.96%. LRMS: m/z 372.2 (M+1)+.

Sources & evidence

ORD record
ord-3e71857160214fa1b0e535b4c84286af
Source dataset
uspto-grants-1997_03
Patent number
US05607960

Reaction notes

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