1,2-Dibromoethane → HCID 53754834, compound

Participants

Reaction Steps

To a mixture of the above oxime (7.0 g, 29 mmol), 1,2-dibromoethane (50 ml) and N,N,N,N-tetrabutylammonium bromide (1.0 g, 3 mmol) was carefully added 9N sodium hydroxide (33 ml) while the temperature was kept below 20° C. After stirring at ambient temperature for 3 h the phases were separated and the organic phase was washed with water (2×100 ml) and saturated aqueous ammonium chloride (30 ml). The solvent was evaporated in vacuo and the residue co-evaporated in vacuo with absolute ethanol (100 ml) to give 8.1 g of 1,2-bis(2-fluorophenyl)ethanone O-(2-bromoethyl)oxime.

Provenance & Evidence