Triethyl phosphite → HCID 19972027, compound

Participants

Reaction Steps

A solution of the bromide 7 (195 mg; 0.38 mmol) and triethyl phosphite (130 μl; 0.76 mmol) in abs. THF (50 ml) is concentrated under reduced pressure after stirring at room temperature for 4 hours. A mixture of the diastereomeric phosphinic acid esters 14 (145 mg, 64% of theory after recrystallization from ethyl acetate) is obtained.

Provenance & Evidence