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HRID975709

反应详情

EQUATION

反应方程式

HRID 975709 的结构方程式

REACTANTS

反应物

3
结构：CC(C)(C)[O-].[K+]
HCID23665647

2-Methyl-2-propanol, potassium salt

C4H9KO

结构：C=CCOC(=O)N1C[C@H](OS(C)(=O)=O)C[C@H]1CCn1cncc1CO
HCID54381297

未命名化合物

结构：CC(O)=S
HCID178418634

未命名化合物

PRODUCTS

生成物

1
结构：C=CCOC(=O)N1C[C@@H](SC(C)=O)C[C@H]1CCn1cncc1CO
HCID54235556

未命名化合物

PROCEDURE

实验过程

(2R,4R)-1-Allyloxycarbonyl-2-[2-(5-hydroxymethyl-imidazol-1-yl) ethyl]-4-methanesulfonyloxypyrrolidine (1.63 g) was reacted with thioacetic acid (0.65 ml) and potassium t-butoxide (0.978 g) in substantially the same manner as that of Preparation 14-12) to give (2R,4S)-1-allyloxycarbonyl-4-acetylthio-2-[2-(5-hydroxymethyl-imidazol-1-yl)ethyl]pyrrolidine (884 mg) as an orange paste.

WORKUP

后处理

  1. customof Preparation 14-12)