Methanesulfonic Acid → HCID 19968402, compound

Participants

Reaction Steps

A solution of methanesulphonic acid (0.3 g) in ether (15 ml) was added dropwise to a cooled solution of 5-(4-chlorophenyl)-1-azaspiro[5.5]undec-4-ene (0.8 g, prepared in a similar manner to that described in Example 14) in ether (25 ml). The resulting solid was collected by filtration, washed with ether and dried in vacuo at ambient temperature to yield 5-(4-chlorophenyl)-1-azaspiro[5.5]undec-4-ene methanesulphonate as a white solid. Yield 1.0 g, mp 226°-231.5° C.

Provenance & Evidence