HuagongsheHuagongshe Chemistry Print Report · For research reference only
12-[(Propan-2-yl)sulfanyl]dodecanoic acid → 17-(12-(Isopropylthio)dodecanoyloxy)-4-methyl-5alpha-4-azaandrostan-3-on
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 12-[(Propan-2-yl)sulfanyl]dodecanoic acid | HCID 18796280 | — |
| Reactant | 17-Hydroxy-4-methyl-5a-4-azaandrostan-3-one | HCID 22862542 | — |
| Reactant | 20-Hydroxy-4-methyl-5a-4-azapregnan-3-one | HCID 22862566 | — |
| Reactant | HCID 178443212 | HCID 178443212 | — |
| Product | 17-(12-(Isopropylthio)dodecanoyloxy)-4-methyl-5alpha-4-azaandrostan-3-on | HCID 22870644 | — |
Reaction Steps
Employing substantially the same procedure as described in Example 1, but substituting 17-hydroxy-4-methyl-5α-4-azaandrostan-3-one and 12-(isopropylthio)dodecanoic acid for the 20-hydroxy-4-methyl-5α-4-azapregnan-3-one and 11-ethylthioundecanoic acid, respectively, used therein, the title compound was obtained. MS M+ calculated for C34H59NO3S, mw=561.92; observed m/e 561.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05610162 |
| Source dataset | uspto-grants-1997_03 |
| ORD ID | ord-bf37bd2f359f45a4a8175942f3c5f5c4 |
| Source note | uspto-grants-1997_03 |