反应详情

A mixture of 1.9 g of 6-[(2-biphenylcarbonyl)amino]pyridine-3-carboxylic acid and 9 ml of thionyl chloride is refluxed for 1 hour and then concentrated to dryness under vacuum. Toluene (15 ml) is added (twice) to the residue and the solvent removed under vacuum to give 2.1 g of a light brown oil.

1. temperatureis refluxed for 1 hour
2. concentrationconcentrated to dryness under vacuum
3. additionToluene (15 ml) is added (twice) to the residue
4. customthe solvent removed under vacuum