5-Benzyloxy-8-fluoro-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid → 5-benzyloxy-N-[(4-dimethylaminophenyl)methyl]-8-fluoro-N-(4-isopropylphenyl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide

HRID 97590Notes

Reaction equation

HRID 97590 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[c:10]2[c:15]([c:16]([F:19])[cH:17][cH:18]1)[CH:14]([C:20](=[O:21])[OH:22])[CH2:13][CH2:12][CH2:11]2.[CH3:23][N:24]([c:25]1[cH:26][cH:27][c:28]([CH2:31][NH:32][c:33]2[cH:34][cH:35][c:36]([CH:39]([CH3:40])[CH3:41])[cH:37][cH:38]2)[cH:29][cH:30]1)[CH3:42]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[c:10]2[c:15]([c:16]([F:19])[cH:17][cH:18]1)[CH:14]([C:20](=[O:21])[N:32]([CH2:31][c:28]1[cH:27][cH:26][c:25]([N:24]([CH3:23])[CH3:42])[cH:30][cH:29]1)[c:33]1[cH:34][cH:35][c:36]([CH:39]([CH3:40])[CH3:41])[cH:37][cH:38]1)[CH2:13][CH2:12][CH2:11]2

Participants

3

Reactant 2

HCID 178545405-Benzyloxy-8-fluoro-1,2,3,4-tetrahydronaphthalene-1-carboxylic acidHCID 21957887N-(4-(Dimethylamino)benzyl)-4-isopropylbenzenamine

Product 1

HCID 595973645-benzyloxy-N-[(4-dimethylaminophenyl)methyl]-8-fluoro-N-(4-isopropylphenyl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide

Sources & evidence

ORD record
ord-463a400b55b7441b9cc17811d39de85f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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