HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-{[(3-Methylphenyl)carbamoyl]amino}acetic acid → HCID 131719903, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-{[(3-Methylphenyl)carbamoyl]amino}acetic acid | HCID 14996960 | — |
| Reactant | HCID 15374578 | HCID 15374578 | — |
| Solvent | 1,2-Dichloroethane | HCID 11 | — |
| Solvent | Thionyl Chloride | HCID 24386 | — |
| Product | HCID 131719903 | HCID 131719903 | 29.2% |
Reaction Steps
By proceeding in a fashion similar to that described in Example 1 but starting from 2.2 g of ethyl (2RS,5SR)-5-phenylprolinate, 2.1 g of 2-[3-(3-methylphenyl)ureido]acetic acid in suspension in 50 cm3 of anhydrous 1,2-dichloroethane and 0.72 cm3 of sulphinyl chloride, 1.2 g of ethyl (2RS,5SR)-1-{2-[3-(3-methylphenyl)ureido]acetyl}-5-phenylprolinate, melting at 115° C., are obtained after recrystallization in acetonitrile.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05610144 |
| Source dataset | uspto-grants-1997_03 |
| ORD ID | ord-a76ea087e14c482996014311f5cb7ed4 |
| Source note | uspto-grants-1997_03 |