Trimethylsilyl iodide → HCID 11044929, compound

Participants

Reaction Steps

tert-Butyl (2S,5R)-1-(2-aminoacetyl)-5-phenylprolinate may be obtained in a fashion similar to that described in Example 2 A, but starting from 1.22 g of tert-butyl (2S,5R)-1-(2-tert-butoxycarbonylaminoacetyl)-5-phenylprolinate, 0.45 cm3 of iodotrimethylsilane in solution in 30 cm3 of anhydrous chloroform. 0.79 g of tert-butyl (2S,5R)-1-(2-aminoacetyl)-5-phenylprolinate is thus obtained in the form of an oil, used as it is in subsequent syntheses.

Provenance & Evidence