HRID976034

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6054

2-Phenylethanol

C8H10O

HCID145486

未命名化合物

PRODUCTS

生成物

HCID383145

2-Phenylethyl 3-(3,4-difluorophenyl)-2-propenoate

C17H14F2O2

收率 38%

PROCEDURE

实验过程

Reaction of 3,4-difluorocinnamic acid and β-phenylethyl alcohol as outlined in method A provided 67J-17-A as snow-white crystals (38% yield): mp 53°-57° C., 1H NMR (CDCl3) δ:7,49 (d, 1H, J=16 Hz), 7.30-7.05 (m, 8H) 6.27 (d, 1H, J=16 Hz), 4.36 (t, 2H, J=7.0 Hz), 3.82 (s, 3H), 2.95 (t, 2H, J=7.0 Hz); FABMS (NBA, +VE m/z 289 (M+H). Anal. (C17H14O2F2) C,H.