HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → (Dibenzyl)acetyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | Benzenepropanoic acid, alpha-(phenylmethyl)- | HCID 64800 | — |
| Product | (Dibenzyl)acetyl chloride | HCID 12394381 | 94.1% |
Reaction Steps
To 20 mL of SOCl2 was added in portions 3.14 g (13.1 mmol) of di-benzylacetic acid and the solution stirred at room temperature overnight. The SOCl2 was removed under reduced pressure and the residue taken up in Et2O and the solvent removed again. There was obtained 3.18 g (94.1% yield) of the product as an oil. The structure was confirmed by NMR spectroscopy.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05610177 |
| Source dataset | uspto-grants-1997_03 |
| ORD ID | ord-ab89ef045e2e4027a423d7a5c5ba4430 |
| Source note | uspto-grants-1997_03 |