Pyridine → HCID 19966546, compound

HRID 976214Notes

Reaction equation

HRID 976214 reaction equation
[CH2:1]([Cl:4])[CH:2]=[CH2:3].[N:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1>O>[CH2:1]([Cl:4])[CH:2]=[CH2:3].[NH+:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1

Participants

4

Reactant 2

HCID 1049PyridineHCID 7850Allyl chloride

Product 1

HCID 19966546HCID 19966546, compoundYield 90%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
50 °C

Procedure

466.5 g of water are placed in the reactor. 229.5 g (3 mol) of allyl chloride are added and the mixture is heated to 50° C. 237.0 g (3 mol) of pyridine are then added dropwise over a period of one hour with vigorous stirring. Following a further eight hours at 50° C. the reaction mixture is subjected to steam distillation at 500 mbar/80° C. During the steam distillation the pH is kept at 5 by means of dilute NaOH. Distillation is continued until the content of pyridine in the bottoms is less than 0.1%. The yield is 90%.

Workup

  1. distillationthe reaction mixture is subjected to steam distillation at 500 mbar/80° C
  2. distillationDuring the steam distillation the pH
  3. distillationDistillation

Sources & evidence

ORD record
ord-5c17443a24064877adf94e336f2f3ee4
Source dataset
uspto-grants-1997_03
Patent number
US05611906

Reaction notes

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