Hydrochloric Acid → HCID 19966720, compound

Participants

Reaction Conditions

Reaction Steps

10.2 g of n-Butyl isocyanate (0.10 mol) were added dropwise at 25° C. to a suspension of 20.1 g of 2-(methylsulfinyl)benzenesulfonamide (0.09 mol) in 250 ml of acetonitrile. 13.9 g of potassium carbonate (0.10 mol) were added, after which the refluxing mixture was stirred for 4 hours. After cooling to 0° C., the mixture was poured onto 400 ml ice/water, brought to a pH of 1 by adding concentrated hydrochloric acid and extracted with methylene chloride. The organic extracts were washed neutral with water and dried. After removal of the solvent, 25 g of the title compound (85% of theory) were obtained as a pale brown oil.

Provenance & Evidence