HCID 54077336, compound → HCID 18974399, compound

Participants

Reaction Steps

A solution of 10.3 g (37.5 mmol) of methyl (4-benzyloxy-1,3-dimethylpyrazol-5-yl)acetate in 200 ml of methanol is hydrogenated in the presence of 1 g of 10% Pd/C. When the reaction is complete, the reaction mixture is filtered and the filtrate is concentrated under vacuum. The residue is recrystallised from dichloromethane/n-hexane, giving methyl (1,3-dimethyl-4-hydroxypyrazol-5-yl)acetate; m.p. 119°-120° C.

Provenance & Evidence