HCID 19036658, compound → HCID 86750581, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of the product of step B (2.71 g, 6.35 mmol) in dry THF (50 mL) at -78° C. under an atmosphere of nitrogen was added a 0.1 M solution of SmI2 (135 mL, 13.5 mmol) over 10 minutes. The blue solution was stirred at -78° C. for 1 hour, poured into dilute ag. HCl, extracted with EtOAc, washed with sat'd NaHCO3, dried (MgSO4), filtered, and the solvent evaporated under reduced pressure. Silica gel chromatography (35-50% EtOAc/hexane) afforded 1.90 g (86% ) of title product.

Provenance & Evidence