Hydrochloric Acid → HCID 19967162, compound

Participants

Reaction Conditions

Reaction Steps

A 10% aqueous solution of hydrochloric acid was added to 30 ml of a solution of 2.4 g of 3-formyl-5,6,7,8-tetrahydro-2-methoxymethoxy-5,5,8,8-tetramethylnaphthalene in tetrahydrofuran at room temperature. The obtained mixture was stirred at 50° C. for 4 hours, followed by the addition thereto of 30 ml of water. The obtained mixture was extracted with ethyl acetate. The organic phase was washed with a saturated aqueous solution of common salt, dried over anhydrous magnesium sulfate and distilled to removd the solvent. The residue was purified by silica gel chromatography (developer: 10% diethyl ether/n-hexane) to give 1.8 g of the title compound as a colorless oil.

Provenance & Evidence