HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 3-Methylbenzo[b]thiophene-2-acetyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 3-Methylbenzo[b]thiophene-2-acetic acid | HCID 2779867 | — |
| Product | 3-Methylbenzo[b]thiophene-2-acetyl chloride | HCID 21837034 | — |
Reaction Steps
A mixture of 2.0 g of 3-methylbenzo[b]-thiophene-2-acetic acid and 19.4 ml of thionyl chloride is heated at reflux for 1 hour. The volatiles are evaporated in vacuo to give a residue which is concentrated from toluene three times and dried under vacuum to give 2.25 g of the desired product as a residue.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05612334 |
| Source dataset | uspto-grants-1997_03 |
| ORD ID | ord-6a83558c61944570a0247cabd93249bf |
| Source note | uspto-grants-1997_03 |