Ethyl (7-methoxynaphthalen-1-yl)acetate → 2-(7-Methoxynaphthalen-1-yl)acetic acid

HRID 976451Notes

Reaction equation

HRID 976451 reaction equation
[CH3:1][O:2][C:3]1[CH:12]=[C:11]2[C:6]([CH:7]=[CH:8][CH:9]=[C:10]2[CH2:13][C:14]([O:16]CC)=[O:15])=[CH:5][CH:4]=1>[OH-].[Na+].C(O)C>[CH3:1][O:2][C:3]1[CH:12]=[C:11]2[C:6]([CH:7]=[CH:8][CH:9]=[C:10]2[CH2:13][C:14]([OH:16])=[O:15])=[CH:5][CH:4]=1

Participants

4

Reactant 1

HCID 13570063Ethyl (7-methoxynaphthalen-1-yl)acetate

Product 1

HCID 135701052-(7-Methoxynaphthalen-1-yl)acetic acid

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 14798Sodium HydroxideSolvent

Procedure

A mixture of ethyl (7-methoxynaphth-1-yl)acetate obtained above in 250 cm3 of sodium hydroxide at 20% in ethanol is refluxed for 3 hours.

Workup

  1. temperatureis refluxed for 3 hours

Sources & evidence

ORD record
ord-62c17be87db34ce994e0076b6be80b06
Source dataset
uspto-grants-1997_03
Patent number
US05612368

Reaction notes

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