Iodoacetyl chloride → HCID 19967266, compound

HRID 976458Notes

Reaction equation

[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:9](=[CH:10][CH:11]=1)[NH:8][CH:7]=[C:6]2[CH2:12][O:13][NH:14][C:15](=[O:17])[CH3:16].[I:18]CC(Cl)=O>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:9](=[CH:10][CH:11]=1)[NH:8][CH:7]=[C:6]2[CH2:12][O:13][NH:14][C:15](=[O:17])[CH2:16][I:18]

Participants

Reactant 2

HCID 3084680Iodoacetyl chloride

HCID 19967292HCID 19967292, compound

Product 1

HCID 19967266HCID 19967266, compound

Procedure

By carrying out the procedure in the same manner as for the synthesis of the compound of Example 13, but replacing the acetic acid chloride with iodoacetic acid chloride, the title compound is obtained.

Sources & evidence

ORD record: ord-e4c01775ab15446a818a3e39b2a2154e
Source dataset: uspto-grants-1997_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05612368

Reaction notes

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