HCID 21468914, compound → HCID 21468845, compound

HRID 976559Notes

Reaction equation

HRID 976559 reaction equation
[C:1]([C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[C:9]1[CH:15]=[CH:14][C:12]([NH2:13])=[C:11]([N+:16]([O-])=O)[CH:10]=1)#[N:2]>C(O)C.[Pd]>[NH2:16][C:11]1[CH:10]=[C:9]([C:4]2[CH:5]=[CH:6][CH:7]=[CH:8][C:3]=2[C:1]#[N:2])[CH:15]=[CH:14][C:12]=1[NH2:13]

Participants

4

Reactant 1

HCID 21468914HCID 21468914, compound

Product 1

HCID 21468845HCID 21468845, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

4-(2-Cyanophenyl)-2-nitroaniline (0.042 moles,10 g.) was dissolved in 200 ml ethanol and hydrogenated at 40 psi over 10 g of 10% Pd/C. The solution was filtered, concentrated, and purified by HPLC eluted with a gradient of 0-50% ethyl acetate in toluene. (MS)

Workup

  1. filtrationThe solution was filtered
  2. concentrationconcentrated
  3. custompurified by HPLC
  4. washeluted with a gradient of 0-50% ethyl acetate in toluene

Sources & evidence

ORD record
ord-3dd3997ddcb1495f842d5f0883b96f6c
Source dataset
uspto-grants-1997_03
Patent number
US05612360

Reaction notes

Loading…