Isocyanate → HCID 19967396, compound

HRID 976650Notes

Reaction equation

HRID 976650 reaction equation
[CH2:1]([C:8]1[CH:16]=[CH:15][C:11](C(O)=O)=[CH:10][CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[N-:17]=[C:18]=[O:19].[CH2:20]([CH:22]([NH:25][OH:26])[CH2:23][CH3:24])[CH3:21]>>[OH:26][N:25]([CH:22]([CH2:23][CH3:24])[CH2:20][CH3:21])[C:18]([NH:17][C:11]1[CH:10]=[CH:9][C:8]([CH2:1][C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=2)=[CH:16][CH:15]=1)=[O:19]

Participants

4

Reactant 3

HCID 105034IsocyanateHCID 1364294-Benzylbenzoic acidHCID 19073513N-(pentan-3-yl)hydroxylamine

Product 1

HCID 19967396HCID 19967396, compound

Procedure

Using the method of Compound 76, 4-benzylbenzoic acid (1.93 g, 9 mmole) was converted to the corresponding isocyanate then reacted with N-(1-ethylpropyl)hydroxylamine (1.4 g, 14 mmole) to provide 1.9 g of the desired product as off-white crystals, m.p. 132.5°-134.1° C. Analysis: Calculated for C19H24N2O2 : %C, 73.05; %H, 7.74; %N, 8.97; Found: %C, 72.82; %H, 7.82; %N, 8.79.

Sources & evidence

ORD record
ord-f99cb231641742539085020a783840c0
Source dataset
uspto-grants-1997_03
Patent number
US05612377

Reaction notes

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