4-Benzoylbenzoic acid → HCID 19967376, compound

HRID 976651Notes

Reaction equation

HRID 976651 reaction equation
[C:1]([C:9]1[CH:17]=[CH:16][C:12](C(O)=O)=[CH:11][CH:10]=1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[N-:18]=[C:19]=[O:20].[CH2:21]([CH:23]([NH:26][OH:27])[CH2:24][CH3:25])[CH3:22]>>[OH:27][N:26]([CH:23]([CH2:24][CH3:25])[CH2:21][CH3:22])[C:19]([NH:18][C:12]1[CH:11]=[CH:10][C:9]([C:1](=[O:8])[C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=2)=[CH:17][CH:16]=1)=[O:20]

Participants

4

Reactant 3

HCID 691474-Benzoylbenzoic acidHCID 105034IsocyanateHCID 19073513N-(pentan-3-yl)hydroxylamine

Product 1

HCID 19967376HCID 19967376, compound

Procedure

Using the method of Compound 76, 4-benzoylbenzoic acid (1.47 g, 6.5 mmole) was converted to the corresponding isocyanate then reacted with N-(1-ethylpropyl)hydroxylamine (1.0 g, 10 mmole) to provide 0.58 g of the desired product as white crystals, m.p. 156°-157° C. Analysis: Calculated for C19H22N2O3 : %C, 69.92; %H, 6.79; %N, 8.58; Found: %C, 69.7; %H, 6.61; %N, 8.64.

Sources & evidence

ORD record
ord-40198c7a956247db8f3b5651c1e6cfb2
Source dataset
uspto-grants-1997_03
Patent number
US05612377

Reaction notes

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