Sodium Hydroxide → HCID 19964385, compound

HRID 977072Notes

Reaction equation

HRID 977072 reaction equation
[O:1]=[C:2]1[C:11]2[CH:12]=[CH:13][CH:14]=[CH:15][C:10]=2[C:9]([CH2:16][CH2:17][C:18]([O:20]C)=[O:19])=[C:8]2[N:3]1[CH2:4][CH2:5][C:6]1[CH:25]=[CH:24][CH:23]=[CH:22][C:7]=12.[OH-].[Na+]>C(O)C>[O:1]=[C:2]1[C:11]2[CH:12]=[CH:13][CH:14]=[CH:15][C:10]=2[C:9]([CH2:16][CH2:17][C:18]([OH:20])=[O:19])=[C:8]2[N:3]1[CH2:4][CH2:5][C:6]1[CH:25]=[CH:24][CH:23]=[CH:22][C:7]=12

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 15385076HCID 15385076, compound

Product 1

HCID 19964385HCID 19964385, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

2.45 g (7.35 mmol) of methyl 8-oxo-5,8-dihydro-6H-dibenzo[a,g]quinolizine-13-propanoate dissolved in 40 ml of ethanol are introduced into a 100 ml round-bottomed flask, 2 ml of aqueous 30% sodium hydroxide are added and the mixture is heated at reflux for 3 h.

Workup

  1. additionare introduced into a 100 ml round-bottomed flask
  2. temperaturethe mixture is heated
  3. temperatureat reflux for 3 h.

Sources & evidence

ORD record
ord-120cd6fa5ae34aa489202dddceb0a037
Source dataset
uspto-grants-1997_03
Patent number
US05614517

Reaction notes

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