HCID 86750594, compound → HCID 19964384, compound

HRID 977075Notes

Reaction equation

HRID 977075 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]2[C:15](/[CH:16]=[CH:17]/[C:18]([O:20][CH3:21])=[O:19])=[C:14]3[N:9]([CH2:10][CH2:11][C:12]4[CH:25]=[CH:24][CH:23]=[CH:22][C:13]=43)[C:8](=[O:26])[C:7]=2[CH:27]=1>C(O)(=O)C.[Pd]>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]2[C:15]([CH2:16][CH2:17][C:18]([O:20][CH3:21])=[O:19])=[C:14]3[N:9]([CH2:10][CH2:11][C:12]4[CH:25]=[CH:24][CH:23]=[CH:22][C:13]=43)[C:8](=[O:26])[C:7]=2[CH:27]=1

Participants

4

Reactant 1

HCID 86750594HCID 86750594, compound

Product 1

HCID 19964384HCID 19964384, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 176Acetic AcidSolvent

Procedure

To a solution of 3.5 g (9.68 mmol) of methyl (E)-3-(10-methoxy-8-oxo-5,8-dihydro-6H-dibenzo[a,g]quinolizin-13-yl)prop-2-enoate in 100 ml of acetic acid is added 0.5 g of 5% palladium on charcoal and the suspension is subjected to hydrogenation in a Parr apparatus at a pressure of about 0.32 MPa between 50° and 60° C. for 3 h.

Sources & evidence

ORD record
ord-04fcf7b84c164d10ad93d80410566938
Source dataset
uspto-grants-1997_03
Patent number
US05614517

Reaction notes

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