Sodium Hydroxide → HCID 19964381, compound

HRID 977076Notes

Reaction equation

HRID 977076 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]2[C:15]([CH2:16][CH2:17][C:18]([O:20]C)=[O:19])=[C:14]3[N:9]([CH2:10][CH2:11][C:12]4[CH:25]=[CH:24][CH:23]=[CH:22][C:13]=43)[C:8](=[O:26])[C:7]=2[CH:27]=1.[OH-].[Na+]>C(O)C>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]2[C:15]([CH2:16][CH2:17][C:18]([OH:20])=[O:19])=[C:14]3[N:9]([CH2:10][CH2:11][C:12]4[CH:25]=[CH:24][CH:23]=[CH:22][C:13]=43)[C:8](=[O:26])[C:7]=2[CH:27]=1

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 19964384HCID 19964384, compound

Product 1

HCID 19964381HCID 19964381, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

3.4 g (9.36 mmol) of methyl 10-methoxy-8-oxo-5,8-dihydro-6H-dibenzo[a,g]quinolizine-13-propanoate dissolved in 50 ml of ethanol are introduced into a 100 ml round-bottomed flask, 3 ml of aqueous 30% sodium hydroxide are added and the mixture is heated at reflux for 3 h.

Workup

  1. additionare introduced into a 100 ml round-bottomed flask
  2. temperaturethe mixture is heated
  3. temperatureat reflux for 3 h.

Sources & evidence

ORD record
ord-b6ea32b54f8143af880ee246a708e24d
Source dataset
uspto-grants-1997_03
Patent number
US05614517

Reaction notes

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