HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 977200Generated: October 26, 2026
Piperidine → 5-[(3,4-Dihydroxy-5-nitrophenyl)methylidene]-4-thioxothiazolidin-2-one
https://huagongshe.com/reaction/977200
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | 4-Sulfanylidene-1,3-thiazolidin-2-one | HCID 1539595 | — |
| Reactant | 3,4-Dihydroxy-5-nitrobenzaldehyde | HCID 5748957 | — |
| Solvent | Acetic acid 10-acetoxymethyl-anthracen-9-ylmethyl ester | HCID 613145 | — |
| Product | 5-[(3,4-Dihydroxy-5-nitrophenyl)methylidene]-4-thioxothiazolidin-2-one | HCID 136058947 | — |
Reaction Steps
A solution containing 0.67 g (0.005 mol) of 4-thioxothiazolidin-2-one, 0.92 g (0.005 mol) of 3,4-dihydroxy-5-nitrobenzaldehyde and 0.05 ml of piperidine in 10 ml of acetic was heated for 8 h at 100° C. The product was filtered and washed with 2-propanol. Yield 1.14 g (76.5%), mp >350° C. (decomp.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US05614541 |
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| Source dataset | uspto-grants-1997_03 |
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| ORD ID | ord-bc7f4ba644324b02b4544684d4187c82 |
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| Source note | uspto-grants-1997_03 |
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